NMR- Solvents

Here you can find physical properties for some deuterated solvents:


Degree of Deuteration

Degree of deuteration [%] 99 99.5 99.8 99.95
Remaining concentration of protons [mol/l] 0.1 – 0.06 0.05 – 0.03 0.02 – 0.01 0.006 – 0.003
Advisable concentration of substance [mol/l] 0.1 0.05 0.02 0.005



  1. Ajibade Adebola says:

    Is there any effect of changing solvents on the result?. I’m working on methanolic algal extract and I intend using chloroform as solvent for NMR due to the unavailability of methanol at the moment. Will there be any negative effect on my result?.

  2. Steffen says:

    In general, chemical shifts are solvent dependent. The sign and the value of the change in chemical shifts can are different. Dependent from solvent and substance.

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